structure of 68528-80-3

Suberic Acid Bis(N-Hydroxysuccinimide Ester)

CAS No.: 68528-80-3 Brand: MolBest
M. Ft.: C16H20N2O8 Cat. No: G1857364
M. Wt.: 368.34 MDL: MFCD00049059
Storage: 2-8°C
Purity Grade Package Stock Price Quantity
98% RG 250MG In Stock 3 USD
98% RG 1G In Stock 5 USD
98% RG 5G In Stock 18 USD
98% RG 100G In Stock 249 USD
98% RG 500G In Stock 1749 USD
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Applications of 68528-80-3

Disuccinimidyl suberate is widely used in several applications:

  • Cross-Linking Proteins: It is employed to chemically cross-link proteins prior to cell lysis and immunoprecipitation, enhancing the stability of protein complexes.
  • Bioconjugation: The reagent facilitates the creation of bioconjugates through single-step reactions.
  • Mass Spectrometry: In cross-linking mass spectrometry, it provides insights into protein structure and interactions by stabilizing transient complexes .
  • Cell Surface Cross-Linking: While primarily used for intracellular applications, it can also be adapted for cell-surface cross-linking when combined with water-soluble analogs like bis(sulfosuccinimidyl)suberate .

Biological Activity of 68528-80-3

Disuccinimidyl suberate exhibits significant biological activity by enabling the stabilization of protein interactions and facilitating the creation of bioconjugates. Its ability to cross-link proteins allows researchers to "fix" transient interactions, which can be crucial for studying complex biological processes . For instance, studies have demonstrated its use in cross-linking hemoglobin and bovine serum albumin, yielding stable protein complexes with altered functional properties .

NMR spectrum of 68528-80-3

Physical sample testing spectrum (NMR) of 68528-80-3

Safety Information of 68528-80-3

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Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H312 Harmful in contact with skin
H332 Harmful if inhaled

Safety Data Sheet

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Purchase Instructions of 68528-80-3

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