structure of 70-00-8

1-((2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl)-5-(Trifluoromethyl)Pyrimidine-2,4(1H,3H)-Dione(CAS 70-00-8)

CAS No.: 70-00-8 Brand: MolBest
M. Ft.: C10H11F3N2O5 Cat. No: G6066085
M. Wt.: 296.2 MDL: MFCD00006534
Storage: 2-8°C,Under inert gas. Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
98%
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RG 100MG In Stock 17 USD
98%
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RG 250MG In Stock 30 USD
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RG 1G In Stock 78 USD
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RG 5G In Stock 457 USD
98%
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RG 25G In Stock 2193 USD
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Applications of 70-00-8

Trifluridine is primarily used in ophthalmology as an antiviral treatment. Its applications include:

  • Topical Ophthalmic Solutions: Used for treating infections caused by herpes simplex viruses.
  • Anticancer Treatments: In combination therapies for certain cancers, particularly when used with thymidine phosphorylase inhibitors like tipiracil to enhance bioavailability.

Physical and chemical properties of 70-00-8

Acidity coefficient

pKa 7.85 (Uncertain)

Decomposition

When heated to decomposition, material emits toxic fumes of /hydrogen fluoride/ and /nitrogen oxides/.

Density

1.6±0.1 g/cm3

Exact Mass

296.062012

Index of Refraction

1.534

LogP

-0.7

Melting Point

186 - 189 °C

Merck

14,9687

Molecular Formula

C10H11F3N2O5

Molecular Weight

296.200

PSA

104.55000

Solubility

6.69e+00 g/L

Stability

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.

Storage condition

−20°C

Vapour Pressure

2.52X10-13 mm Hg at 25 °C (est)

Spectrums of 70-00-8

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 70-00-8

Retrosynthesis analysis of 70-00-8


Q&A for CAS 70-00-8

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Download SDS of 70-00-8

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H312 Harmful in contact with skin
H332 Harmful if inhaled
H351 Suspected of causing cancer

Safety Data Sheet

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Operate under the ISO 9001 system