structure of 70-58-6

5-Fluoronicotinamide(CAS 70-58-6)

CAS No.: 70-58-6 Brand: MolBest
M. Ft.: C6H5FN2O Cat. No: G2558931
M. Wt.: 140.12 MDL: MFCD00160352
Storage: Store in a dark,dry area. Use: For laboratory research use only
HS CODE: 2933399090
Purity Grade Package Stock Price Quantity
97%
Documents:COASDS
RG 1G In Stock 17 USD
97%
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RG 5G In Stock 53 USD
97%
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RG 25G In Stock 168 USD
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Applications of 70-58-6

Industry Application Process
Pesticides Herbicide intermediate (e.g., for synthesis of flumioxazin) Prepared via multi-step reactions—including substitution, hydrolysis, and condensation—with halogenated arenes such as 2-chloro-5-(trifluoromethyl)pyridine
Pharmaceuticals Antitumor drug intermediate (e.g., structural modification unit in EGFR inhibitors) Used as a fluorinated heterocyclic building block in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) or nucleophilic substitution to introduce fluorinated motifs into drug scaffolds
Organic Synthesis Key building block for synthesizing fluorinated fine chemicals Employed to construct fluorinated nicotinamide derivatives, followed by functional group transformations—including bromination, nitration, reduction, or N-alkylation—to produce functional materials or analytical standards

Physical and chemical properties of 70-58-6

Boiling Point

256.7ºC at 760mmHg

Density

1.327g/cm3

Exact Mass

140.03900

Flash Point

109ºC

Index of Refraction

1.542

LogP

1.01990

Melting Point

174 - 176°C

Molecular Formula

C6H5FN2O

Molecular Weight

140.11500

PSA

55.98000

Solubility

DMSO (Slightly), Methanol (Slightly)

Storage condition

2-8°C

Retrosynthesis analysis of 70-58-6


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Download SDS of 70-58-6

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Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Operate under the ISO 9001 system