Mitoxantrone hydrochloride(CAS 70476-82-3)
UN No.:
UN 3249
| Purity | Grade | Package | Stock | Price | Quantity |
| 98% | RG | 100MG | In Stock | 22 USD
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| 98% | RG | 250MG | In Stock | 44 USD
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| 98% | RG | 1G | In Stock | 125 USD
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| 98% | RG | 5G | In Stock | 879 USD
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| Bulk Packaging | 1KG | substantially lower unit cost than small-pack SKUs. Contact us for a fast quotation. | |||
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Applications of 70476-82-3
Mitoxantrone is primarily used in oncology and neurology:
- Cancer Treatment: It is indicated for acute myeloid leukemia and breast cancer, often in combination with other chemotherapeutic agents.
- Multiple Sclerosis: Mitoxantrone is utilized to manage secondary-progressive multiple sclerosis, slowing disease progression and reducing relapse frequency.
Physical and chemical properties of 70476-82-3
Boiling Point |
805.7ºC at 760 mmHg |
|---|---|
Decomposition |
When heated to decomposition it emits toxic fumes of /nitrogen oxides & hydrochloric acid/. |
Exact Mass |
516.154236 |
Flash Point |
441.1ºC |
LogP |
2.39260 |
Melting Point |
203-5 °C |
Molecular Formula |
C22H30Cl2N4O6 |
Molecular Weight |
517.403 |
PSA |
163.18000 |
Stability |
Mitoxantrone HCl is not photolabile. Exposure of the product to direct sunlight for one month caused no change in its appearance or potency. Mitoxantrone HCl 0.2 mg/ml in sodium chloride 0.9% in polypropylene syringes is reported to be stable for 28 days at 4 & 20 °C & for 24 hr at 37 °C. Mitoxantrone HCl 2 mg/ml in glass vials & drawn into 12 ml plastic syringes exhibited no visual changes & little or no loss by HPLC when stored for 42 days at 4 & 23 °C. ... Mitoxantrone HCl 0.2 mg/ml in sterile water for injection was stable in Parker Micropump PVC reservoirs for 14 days at 4 & 37 °C, exhibiting no loss by HPLC. Mitoxantrone HCl was cultured with human lymphoblasts to determine whether its cytotoxic activity was retained. The soln retained cytotoxicity for 24 hr at 4 °C & room temp. The pH range of max stability is 2-4.5. Mitoxantrone HCl was unstable when the pH was increased to 7.4. |
Storage condition |
2-8°C |
Water Solubility |
Soluble to 5 mM in water and to 75 mM in DMSO |
Spectrums of 70476-82-3
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Retrosynthesis analysis of 70476-82-3
Cas:3179-90-6
Cas:111228-29-6
Cas:141-43-5
Q&A for CAS 70476-82-3
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Yes. Batch COA available matches the actual shipment. COAs shown online are for reference or from previous batches.
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Download SDS of 70476-82-3
Pictograms |
 |
|---|---|
Signal Word |
Danger |
Hazard Statements |
H340 May cause genetic defects H360 May damage fertility or the unborn child |
Safety Data Sheet |
Download COA of 70476-82-3
Operate under the ISO 9001 system
