structure of 7061-54-3

Phloridzin Dihydrate

CAS No.: 7061-54-3 Brand: MolBest
M. Ft.: C21H28O12 Cat. No: G7772150
M. Wt.: 472.44 MDL: No record
Storage: Store under inert gas.
Purity Grade Package Stock Price Quantity
98% RG 250MG In Stock 3 USD
98% RG 1G In Stock 4 USD
98% RG 5G In Stock 5 USD
98% RG 25G In Stock 20 USD
98% RG 100G In Stock 73 USD
98% RG 500G In Stock 342 USD
98% RG 2.5KG In Stock 1677 USD
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Applications of 7061-54-3

Phlorizin dihydrate has several applications, particularly in pharmacology and biochemistry:

  • Diabetes research: As a sodium-glucose transporter inhibitor, it serves as a model compound for studying glucose metabolism and the development of diabetes treatments.
  • Phytochemical studies: Its presence in various plant species makes it a subject of interest in studies related to plant secondary metabolites and their health benefits.
  • Experimental models: Phlorizin is often used in animal models to investigate the effects of glucose transport inhibition on metabolic processes.

Biological Activity of 7061-54-3

Phlorizin dihydrate exhibits significant biological activity, particularly as an inhibitor of sodium-glucose cotransporters SGLT1 and SGLT2. This property makes it relevant in diabetes research, as it reduces renal glucose reabsorption, thereby lowering blood glucose levels. Although phlorizin was once considered for therapeutic use in type 2 diabetes management, its clinical application has diminished due to its rapid conversion to phloretin in the gastrointestinal tract upon oral administration.

In experimental settings, phlorizin has been shown to induce glycosuria (the excretion of glucose in urine) by blocking glucose reabsorption mechanisms within the renal system.

NMR spectrum of 7061-54-3

Physical sample testing spectrum (NMR) of 7061-54-3

Safety Information of 7061-54-3

Pictograms

Signal Word

Warning

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Purchase Instructions of 7061-54-3

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