structure of 7177-48-2

Ampicillin trihydrate(CAS 7177-48-2)

CAS No.: 7177-48-2 Brand: MolBest
M. Ft.: C16H19N3O4S·3H2O Cat. No: G5290891
M. Wt.: 403.45 MDL: MFCD00072036
Storage: 2-8°C Use: For laboratory research use only
HS CODE: 2941101100
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98%
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Applications of 7177-48-2

Industry Application Process
Pharmaceuticals Antibiotic drug for treating infections caused by susceptible bacteria (e.g., respiratory, urinary tract, and skin/soft tissue infections) Used as an active pharmaceutical ingredient (API) in oral or injectable dosage forms (e.g., tablets, capsules, lyophilized injectables)
Pharmaceutical R&D Selective screening marker in microbial culture Added to growth media (e.g., LB medium) as a resistance-selection antibiotic in molecular biology and genetic engineering to screen transformed bacterial strains carrying the ampicillin-resistance gene
Clinical Diagnostics Supporting antimicrobial susceptibility testing Used in vitro for antimicrobial susceptibility testing (e.g., disk diffusion method, MIC determination) to assess bacterial sensitivity to antibiotics

Physical and chemical properties of 7177-48-2

Acidity coefficient

2.5 (COOH)(at 25℃)

Boiling Point

683.9ºC at 760 mmHg

BRN

5399534

Exact Mass

403.141327

Flash Point

367.4ºC

H Bond Acceptors

5

H Bond Donors

3

Index of Refraction

265 ° (C=0.1, H2O)

LogP

1.35

Melting Point

388 to 392 °F (decomposes) (NTP, 1992)

Merck

14,586

Molecular Formula

C16H25N3O7S

Molecular Weight

403.451

Odor

Odorless or has a faint odor characteristic of the penicillins

PSA

165.72000

Solubility

1 to 10 mg/mL at 70 °F (NTP, 1992)

Stability

The stability of ampicillin sodium in soln is concn dependent and decreased as the concn of the drug increases. Ampicillin sodium appears to be especially susceptible to inactivation in soln containing dextrose, which appears to have a catalytic effect on hydrolysis of the drug.

Storage condition

Sealed in dry,2-8°C

Water Solubility

0.1-1 g/100 mL at 21 ºC

Spectrums of 7177-48-2

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 7177-48-2

Retrosynthesis analysis of 7177-48-2

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Download SDS of 7177-48-2

Pictograms

Signal Word

Danger

Hazard Statements

H315 Causes skin irritation
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335 May cause respiratory irritation
H400 Very toxic to aquatic life
H411 Toxic to aquatic life with long lasting effects

Safety Data Sheet

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