structure of 756525-90-3

2,5-Dioxopyrrolidin-1-Yl2,5,8,11,14,17,20,23-Octaoxahexacosan-26-Oate

CAS No.: 756525-90-3 Brand: MolBest
M. Ft.: C22H39NO12 Cat. No: G8186046
M. Wt.: 509.54 MDL: MFCD13184969
Storage: -20°C,Under inert gas.
Purity Grade Package Stock Price Quantity
98% RG 100MG In Stock 22 USD
98% RG 250MG In Stock 37 USD
98% RG 1G In Stock 101 USD
98% RG 5G In Stock 407 USD
98% RG 25G In Stock 814 USD
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Applications of 756525-90-3

m-PEG8-NHS ester has a wide range of applications in biochemical research and pharmaceutical development:

  • Protein Modification: Used for PEGylating proteins to enhance their stability and reduce immunogenicity.
  • Drug Delivery Systems: Serves as a linker in antibody-drug conjugates (ADCs) for targeted therapy.
  • Diagnostic Imaging: Employed in imaging applications due to its ability to improve solubility and reduce aggregation.
  • Nanotechnology: Utilized for coating nanoparticles such as carbon nanotubes and gold nanoshells to enhance biocompatibility.

Biological Activity of 756525-90-3

The biological activity of m-PEG8-NHS ester is primarily linked to its ability to modify proteins and peptides, thereby enhancing their pharmacokinetic properties. PEGylation, the process of attaching polyethylene glycol chains to biomolecules, can improve solubility, reduce immunogenicity, and prolong circulation time in vivo. These modifications have been shown to enhance the therapeutic efficacy of various agents, including peptides used in anti-HIV therapies and other therapeutic applications.

Moreover, studies have indicated that m-PEG8-NHS ester can be utilized in developing antibacterial agents and cytotoxic dendrimers, showcasing its versatility in biomedical research.

NMR spectrum of 756525-90-3

Physical sample testing spectrum (NMR) of 756525-90-3

Safety Information of 756525-90-3

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Bulk Packaging Price Explanation of 756525-90-3

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Purchase Instructions of 756525-90-3

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

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