2-(Trimethylsilyl)Ethoxymethyl Chloride(CAS 76513-69-4)
UN No.:
UN 2920 8 /PG II
| Purity | Grade | Package | Stock | Price | Quantity |
| 95%+(GC),stabilized with 0.1%diisopropylethylamine | RG | 1G | In Stock | 2 USD
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| 95%+(GC),stabilized with 0.1%diisopropylethylamine | RG | 5G | In Stock | 4 USD
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| 95%+(GC),stabilized with 0.1%diisopropylethylamine | RG | 25G | In Stock | 16 USD
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| 95%+(GC),stabilized with 0.1%diisopropylethylamine | RG | 100G | In Stock | 62 USD
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| 95%+(GC),stabilized with 0.1%diisopropylethylamine | RG | 500G | In Stock | 312 USD
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Applications of 76513-69-4
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Protecting group for aliphatic and phenolic hydroxyl groups | Used as a reagent to introduce the SEM protecting group during the synthesis of drug molecules and intermediates, protecting sensitive hydroxyl functionalities from subsequent reaction steps (e.g., oxidation, reduction, nucleophilic substitution), thereby improving route selectivity and yield. |
| Pharmaceutical Chemicals | Protecting group for amino groups | Applied to protect amino groups in nitrogen-containing heterocycles (e.g., imidazole, pyrazole) or amine-based drug molecules, preventing side reactions under acidic or other specific reaction conditions. |
| Biochemistry | Base protection in nucleotide synthesis | Used to protect exocyclic amino or hydroxyl groups on nucleobases (e.g., guanine) during the synthesis of nucleosides, nucleotides, and oligonucleotides, preventing deamination or degradation during phosphorylation or coupling reactions. |
| Agrochemicals | Structural modification of agrochemical molecules | Employed in the research and synthesis of novel active agrochemical ingredients to protect specific functional groups and construct complex molecular frameworks. |
| Materials Chemistry | Synthesis of functional organosilicon materials | Leverages its silane functionality in grafting or capping reactions to synthesize organosilicon precursors with tailored surface properties or solubility characteristics. |
| Organic Synthesis | Laboratory reagent for organic synthesis | Serves as a general-purpose protecting reagent widely used in total synthesis of complex natural products and process development for fine chemicals, particularly in reaction systems requiring acid-stable protecting groups. |
Physical and chemical properties of 76513-69-4
Boiling Point |
182.1±0.0 °C at 760 mmHg |
|---|---|
BRN |
3587289 |
Density |
0.9±0.1 g/cm3 |
Exact Mass |
166.058075 |
Flash Point |
46.7±0.0 °C |
Index of Refraction |
1.413 |
LogP |
2.23 |
Molecular Formula |
C6H15ClOSi |
Molecular Weight |
166.721 |
PSA |
9.23000 |
Sensitivity |
Moisture Sensitive |
Storage condition |
−20°C |
Vapour Pressure |
1.1±0.3 mmHg at 25°C |
Water Solubility |
decomposes |
Spectrums of 76513-69-4
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Retrosynthesis analysis of 76513-69-4
Cas:2916-68-9
Cas:50-00-0
Q&A for CAS 76513-69-4
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Download SDS of 76513-69-4
Pictograms |
  |
|---|---|
Signal Word |
Danger |
Hazard Statements |
H226 Flammable liquid and vapor H314 Causes severe skin burns and eye damage H318 Causes serious eye damage |
Safety Data Sheet |
Download COA of 76513-69-4
Operate under the ISO 9001 system
