Tris(hydroxymethyl)aminomethane(CAS 77-86-1)
| Purity | Grade | Package | Stock | Price | Quantity |
| 99% | RG | 25G | In Stock | 4 USD
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| 99% | RG | 100G | In Stock | 4 USD
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| 99% | specific | 100G | In Stock | 10 USD
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| 99% | RG | 500G | In Stock | 16 USD
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| 99% | RG | 2.5KG | In Stock | 78 USD
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| 99% | specific | 2.5KG | In Stock | 90 USD
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| 99% | RG | 25KG | In Stock | 762 USD
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| 99.5-100.5%,ACS | ACS | 100G | In Stock | 14 USD
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| 99.5-100.5%,ACS | ACS | 500G | In Stock | 31 USD
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| 99.5-100.5%,PT | PT (standard reagent) | 25G | In Stock | 33 USD
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| 99.5-100.5%,PT | PT (standard reagent) | 100G | In Stock | 125 USD
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| 99.5-100.5%,PT | PT (standard reagent) | 500G | In Stock | 601 USD
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| 99.5-100.5%,PT | PT (standard reagent) | 2.5KG | In Stock | 2886 USD
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Available NMR Spectrum
Verified In Stock
Fast Shipping ISO 9001
Quality System
Applications of 77-86-1
| Industry | Application | Process |
|---|---|---|
| Biomedical Research | Buffer component for electrophoresis, DNA/RNA extraction, PCR, and related assays | Formulated into Tris-HCl buffer solutions (pH 7.0–9.0) to maintain stable pH in reaction systems |
| Pharmaceutical Industry | pH adjuster and stabilizer in drug formulations, including injectables, ophthalmic solutions, and protein-based therapeutics | Added to final sterile formulations to control pH within physiologically compatible ranges (e.g., 7.2–7.6) |
| Cosmetics | pH adjuster and skin-conditioning agent in conditioners, shampoos, and skincare products | Neutralized with acid (e.g., hydrochloric acid) prior to incorporation to ensure product pH of 4.5–6.5, supporting skin barrier function |
| Molecular Diagnostics Reagents | Core buffering component in nucleic acid detection kits | Serves as a foundational component in RT-PCR and isothermal amplification (e.g., LAMP) reaction buffers to ensure enzymatic activity and specificity |
| Cell Culture | Supplement for pH adjustment of basal media (e.g., MEM, DMEM) | Used in conjunction with CO₂ equilibrium systems to enhance pH buffering capacity, particularly under low-CO₂ or CO₂-free culture conditions |
Physical and chemical properties of 77-86-1
Acidity coefficient |
8.1(at 25℃) |
|---|---|
Boiling Point |
219-220 °C at 10 mm Hg |
BRN |
741883 |
Decomposition |
When heated to decomposition it emits toxic fumes of /nitrogen oxide/. |
Density |
1.3±0.1 g/cm3 |
Exact Mass |
121.073891 |
Flash Point |
169.7±26.5 °C |
Index of Refraction |
1.544 |
LogP |
log Kow = -1.56 (est) |
Melting Point |
171-172 °C |
Merck |
14,9772 |
Molecular Formula |
C4H11NO3 |
Molecular Weight |
121.135 |
Odor |
SLIGHT, CHARACTERISTIC ODOR |
pH |
pH of 0.1 molar aq soln = 10.4 |
pH Range |
7 - 9 |
PSA |
86.71000 |
Sensitivity |
Hygroscopic |
Stability |
Stable. Incompatible with bases, strong oxidizing agents. Protect from moisture. |
Storage condition |
2-8°C |
Vapour Pressure |
2.2X10-5 mm Hg at 25 °C (est) |
Water Solubility |
550 g/L (25 ºC) |
λmax |
λ: 260 nm Amax: 0.10 λ: 280 nm Amax: 0.08 |
Spectrums of 77-86-1
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Retrosynthesis analysis of 77-86-1
Q&A for CAS 77-86-1
1. How can I verify product quality?
Every batch of our Chemical Reagents is tested to meet ISO 9001 standards. We provide COA & NMR & SDS Provided with each shipment. Batch COA available for verification, and third-party retesting is supported. A full refund is offered if our data is incorrect.
2. What is the delivery time?
Orders from Ready stock / In stock items typically Ships Tomorrow via Fast Shipping via FedEx/DHL/UPS. International deliveries usually arrive within 7 business days, subject to customs clearance.
3. What if the received product doesn’t meet quality standards?
If your Lab Grade Chemical Reagents do not match the Batch COA available, we will issue a replacement or a full refund upon verification.
4. Are hazardous labels included? How is safe shipping ensured?
Hazardous products are labeled and packaged following international regulations. We provide SDS Provided with all hazardous shipments to ensure safe and compliant transport.
5. Do you offer technical support?
Yes. Our Lab Supplier team is available to assist with questions about product usage, storage, Lab Grade requirements, applications, and more.
6. Are volume discounts available?
Yes. For bulk orders of Chemical Reagents, we offer competitive pricing. Submit a quotation request and we’ll provide a tailored offer.
7. Do you provide samples?
Yes, samples are available for selected Lab Grade products. Please submit a request to confirm availability and specifications.
8. Do you have products in stock?
Yes. Items labeled In stock / Ready stock on our website are available for immediate shipment, usually within 1–2 business days. Large packs or custom specifications require lead time confirmation.
9. Can you customize purity or packaging?
Yes. We support customization of Lab Grade purity, packaging size, and special testing requirements. Share your needs and we’ll provide a tailored solution.
10. Is the COA consistent with the shipped batch?
Yes. Batch COA available matches the actual shipment. COAs shown online are for reference or from previous batches.
11. Do you support long-term supply agreements?
Yes. We offer Lab Supplier services for stable batch consistency, pricing agreements, and safety stock for long-term customers to ensure uninterrupted supply.
12. What payment methods do you accept?
We accept Pay Local Currency via bank transfer (T/T), PayPal, and other methods. Credit terms are available for qualified long-term partners.
Download SDS of 77-86-1
Pictograms |
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|---|---|
Signal Word |
Warning |
Hazard Statements |
H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation |
Safety Data Sheet |
Download COA of 77-86-1
Operate under the ISO 9001 system
Cas:114444-46-1
