structure of 77877-19-1

(S)-4-Isopropyl-3-Propionyloxazolidin-2-One

CAS No.: 77877-19-1 Brand: MolBest
M. Ft.: C9H15NO3 Cat. No: G4513656
M. Wt.: 185.22 MDL: MFCD00043401
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
98% RG 250MG In Stock 15 USD
98% RG 1G In Stock 22 USD
98% RG 5G In Stock 77 USD
98% RG 100G In Stock 1955 USD
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Applications of 77877-19-1

The primary applications of (S)-(+)-4-Isopropyl-3-propionyl-2-oxazolidinone are in organic synthesis and pharmaceutical development:

  • Chiral auxiliary: It serves as an excellent chiral auxiliary in asymmetric synthesis, allowing for the creation of new stereogenic centers with high enantioselectivity.
  • Pharmaceutical intermediate: The compound is used in the synthesis of various drug candidates and active pharmaceutical ingredients.
  • Ligand in organometallic chemistry: It can be used as a ligand in metal-catalyzed reactions, providing stereocontrol in various transformations.
  • Template for natural product synthesis: The compound has been employed in the total synthesis of complex natural products, guiding the stereochemistry of key steps.

Biological Activity of 77877-19-1

While (S)-(+)-4-Isopropyl-3-propionyl-2-oxazolidinone itself is not known to have significant direct biological activity, it serves as a crucial intermediate in the synthesis of biologically active compounds. The oxazolidinone core is present in several antibiotics and other pharmaceuticals, contributing to their biological effects.

Some oxazolidinone derivatives have shown potent antibacterial activity against various gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). These compounds work by inhibiting bacterial protein synthesis, specifically by binding to the 50S ribosomal subunit.

NMR spectrum of 77877-19-1

Physical sample testing spectrum (NMR) of 77877-19-1

Safety Information of 77877-19-1

Pictograms

Signal Word

Warning

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Purchase Instructions of 77877-19-1

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