4,4'-Sulfonyldianiline

Dapsone is used in several therapeutic contexts:

• Leprosy Treatment: It is a cornerstone drug in multidrug therapy for leprosy.
• Dermatitis Herpetiformis: Effective in managing this gluten-sensitive skin disorder.
• Acne Vulgaris: Employed topically to treat inflammatory acne.
• Pneumocystis Pneumonia: Used as a prophylactic treatment in immunocompromised patients, particularly those with HIV/AIDS.

Dapsone functions primarily by inhibiting the synthesis of dihydrofolic acid in bacteria, similar to sulfonamides. It competes with para-aminobenzoate for the active site of dihydropteroate synthase, effectively disrupting nucleic acid synthesis in susceptible organisms. This mechanism not only impedes bacterial growth but also has anti-inflammatory effects by inhibiting myeloperoxidase activity in neutrophils, reducing tissue damage during inflammatory responses.

Please email your required order quantity and detailed technical specifications to sales@.
Our sales team will promptly prepare an accurate quotation for your bulk order and provide a comprehensive pricing proposal.

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.