Tetradecanedioic acid

Tetradecanedioic acid has diverse applications across various fields:

• Industrial Chemicals: It serves as an intermediate in the production of polymers and resins.
• Biomarker Research: Its role as a potential biomarker for organic anion-transporting polypeptide interactions positions it as significant in pharmacological studies.
• Chemical Synthesis: It is utilized in synthesizing esters and amides due to its reactivity.

These applications underscore its importance in both industrial and research contexts.

Tetradecanedioic acid is recognized as an endogenous metabolite within the human body and is classified among long-chain fatty acids. It interacts with organic anion-transporting polypeptides (OATPs), influencing the transport and distribution of various substances, including drugs. Tetradecanedioic acid's hydrophobic nature makes it relatively neutral and poorly soluble in water, impacting its biological interactions and pharmacokinetics. Notably, it has been proposed as a candidate biomarker for drug-drug interactions mediated by OATPs.

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