9,10-Difluoro-2,3-Dihydro-3-Methyl-7-Oxo-7H-Pyrido[1,2,3-De]-1,4-Benzoxazine-6-Carboxylic Acid

9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid finds its primary application as an intermediate in the synthesis of fluoroquinolone antibiotics. Additionally:

• Pharmaceuticals: Used in drug development due to its antibacterial properties.
• Research: Employed in studies focused on antibiotic resistance and drug design.

Research indicates that 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid exhibits significant biological activity. It serves as an intermediate in the synthesis of fluoroquinolone antibiotics like ofloxacin and levofloxacin. These antibiotics are known for their broad-spectrum antibacterial properties, particularly against Gram-negative bacteria. The structural features of this compound contribute to its effectiveness in inhibiting bacterial DNA gyrase and topoisomerase IV.

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