7-Chloro-4-Piperazinoquinoline
| Purity | Grade | Package | Stock | Price | Quantity |
|---|---|---|---|---|---|
| 98% | RG | 250MG | In Stock | 4 USD | |
| 98% | RG | 1G | In Stock | 10 USD | |
| 98% | RG | 5G | In Stock | 30 USD | |
| 98% | RG | 100G | In Stock | 452 USD | |
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Applications of 837-52-5
The primary applications of 7-chloro-4-(piperazin-1-yl)quinoline include:
- Pharmaceutical Development: As an intermediate in the synthesis of piperaquine for malaria treatment.
- Cancer Research: Investigated for its potential as an anticancer agent due to its cytotoxic properties against various cancer cell lines.
- Chemical Research: Used as a scaffold for developing new derivatives with enhanced biological activities.
Biological Activity of 837-52-5
7-Chloro-4-(piperazin-1-yl)quinoline exhibits significant biological activities:
- Antimalarial Activity: It is primarily recognized as an intermediate in piperaquine synthesis, which is effective against malaria.
- Cytotoxicity: Studies have shown that derivatives of this compound can inhibit cancer cell lines, such as MCF-7 (breast cancer) and PC3 (prostate cancer), indicating potential applications in oncology.
- Sirtuin Inhibition: The compound acts as a sirtuin inhibitor and has been noted for its ability to inhibit serotonin uptake, with an IC50 value of 50 µM.
NMR spectrum of 837-52-5
Safety Information of 837-52-5
Download COA of 837-52-5
Bulk Packaging Price Explanation of 837-52-5
Please email your required order quantity and detailed technical specifications to sales@.
Our sales team will promptly prepare an accurate quotation for your bulk order and provide a comprehensive pricing proposal.
Purchase Instructions of 837-52-5
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.
These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.
Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.
