structure of 84271-78-3

N-Succinimidyl-S-Acetylthiopropionate

CAS No.: 84271-78-3 Brand: MolBest
M. Ft.: C9H11NO5S Cat. No: G2659094
M. Wt.: 245.25 MDL: MFCD00133023
Storage: 2-8°C
Purity Grade Package Stock Price Quantity
99% RG 100MG In Stock 19 USD
99% RG 250MG In Stock 37 USD
99% RG 1G In Stock 51 USD
99% RG 5G In Stock 197 USD
99% RG 25G In Stock 1802 USD
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Applications of 84271-78-3

The compound has several applications:

  • Medicinal Chemistry: Due to its anticonvulsant properties, it is explored for potential therapeutic uses in treating epilepsy and other neurological disorders.
  • Biochemical Research: Its ability to form covalent bonds with proteins makes it valuable for studying protein interactions and functions.
  • Drug Development: The unique chemical structure allows for modifications that can lead to new derivatives with enhanced biological activities or reduced side effects.

Biological Activity of 84271-78-3

(2,5-dioxopyrrolidin-1-yl) 3-acetylsulfanylpropanoate exhibits notable biological activities, particularly as an anticonvulsant. It acts primarily by inhibiting calcium currents mediated by Cav 1.2 (L-type) channels, which are crucial in neurotransmission and neuronal excitability. This inhibition can disrupt calcium signaling pathways, leading to its anticonvulsant effects observed in various animal seizure models. Additionally, the compound demonstrates high metabolic stability in human liver microsomes, suggesting a favorable pharmacokinetic profile for therapeutic applications.

NMR spectrum of 84271-78-3

Physical sample testing spectrum (NMR) of 84271-78-3

Safety Information of 84271-78-3

Pictograms

Signal Word

Warning

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Purchase Instructions of 84271-78-3

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