2-((Azido-Peg8-Carbamoyl)Methoxy)Acetic Acid

The primary applications of 2-((Azido-PEG8-carbamoyl)methoxy)acetic acid include:

• Bioconjugation: It serves as a linker for attaching various biomolecules such as antibodies, proteins, or nucleic acids.
• Drug Development: Its role in PROTACs highlights its importance in developing targeted therapies for diseases like cancer.
• Diagnostics: The compound can be used in imaging studies due to its ability to conjugate with fluorescent markers or radiolabels.

2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is primarily recognized for its role as a non-cleavable linker in proteolysis targeting chimeras (PROTACs). PROTACs are innovative therapeutic agents designed to induce targeted protein degradation, offering potential advantages over traditional small molecules. The incorporation of this compound into PROTACs enhances their stability and solubility while maintaining the necessary biological activity required for effective target engagement.

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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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