structure of 849217-64-7

N-(3-Fluoro-4-((6-Methoxy-7-(3-Morpholinopropoxy)Quinolin-4-Yl)Oxy)Phenyl)-N-(4-Fluorophenyl)Cyclopropane-1,1-Dicarboxamide(CAS 849217-64-7)

CAS No.: 849217-64-7 Brand: MolBest
M. Ft.: C34H34F2N4O6 Cat. No: G9260261
M. Wt.: 632.65 MDL: No record
Storage: -20°C Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
98%
Documents:COANMRSDS
RG 100MG In Stock 140 USD
98%
Documents:COANMRSDS
RG 250MG In Stock 261 USD
98%
Documents:COANMRSDS
RG 1G In Stock 871 USD
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Applications of 849217-64-7

Foretinib is primarily investigated for its application in oncology as a targeted therapy for various solid tumors. Its ability to inhibit multiple receptor tyrosine kinases makes it suitable for treating cancers with known MET mutations or overexpression. Clinical trials have evaluated its efficacy in conditions like hereditary papillary renal cell carcinoma and other malignancies associated with aberrant MET signaling. Despite its potential, development has faced challenges, leading to discontinuation in some clinical studies as of 2015.

Physical and chemical properties of 849217-64-7

Acidity coefficient

13.14±0.70(Predicted)

Boiling Point

828.5±65.0 °C at 760 mmHg

Density

1.4±0.1 g/cm3

Exact Mass

632.244629

Flash Point

454.8±34.3 °C

Index of Refraction

1.649

LogP

5.12

Melting Point

>98°C (dec.)

Molecular Formula

C34H34F2N4O6

Molecular Weight

632.654

PSA

116.45000

Solubility

DMSO (Slightly), Ethanol (Slightly)

Storage condition

-20°C

Vapour Pressure

0.0±3.0 mmHg at 25°C

Spectrums of 849217-64-7

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 849217-64-7

Retrosynthesis analysis of 849217-64-7


Q&A for CAS 849217-64-7

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Download SDS of 849217-64-7

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Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H373 May causes damage to organs through prolonged or repeated exposure

Safety Data Sheet

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Operate under the ISO 9001 system