structure of 86060-83-5

Fmoc-L-Aspartic Acid-1-Benzyl Ester(CAS 86060-83-5)

CAS No.: 86060-83-5 Brand: MolBest
M. Ft.: C26H23NO6 Cat. No: G2517480
M. Wt.: 445.46 MDL: MFCD00198201
Storage: Store in a cool,dry area. Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
98%
Documents:COANMRLCMSSDS
RG 1G In Stock 4 USD
98%
Documents:COANMRLCMSSDS
RG 5G In Stock 16 USD
98%
Documents:COANMRLCMSSDS
RG 25G In Stock 45 USD
98%
Documents:COANMRLCMSSDS
RG 100G In Stock 140 USD
98%
Documents:COANMRLCMSSDS
RG 500G In Stock 1060 USD
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Applications of 86060-83-5

Industry Application Process
Biopharmaceuticals Side-chain protecting reagent for aspartic acid residues in solid-phase peptide synthesis (SPPS) Used in Fmoc-based SPPS to incorporate aspartic acid residues protected with a benzyl (Bn) ester; the Fmoc group protects the α-amino group, while the benzyl ester protects the β-carboxyl group, enabling selective deprotection and coupling
Pharmaceutical R&D Key building block for synthesizing therapeutic peptides containing aspartic acid sequences (e.g., hormone analogs, antimicrobial peptides, targeting peptides) After Fmoc removal with piperidine on resin-bound growing peptide chains, coupled with the next activated Fmoc-amino acid; benzyl ester protecting groups are cleaved upon completion of synthesis using HBr/trifluoroacetic acid or catalytic hydrogenolysis
Biochemical Research Preparation of site-specific aspartic acid probes labeled with isotopes or fluorescent tags Enables selective derivatization at the side-chain benzyl ester site (e.g., hydrolysis followed by conjugation with fluorescent dyes), followed by hydrogenolysis to yield side-chain functionalized aspartic acid derivatives

Physical and chemical properties of 86060-83-5

Acidity coefficient

4.05±0.19(Predicted)

Boiling Point

683.7±55.0 °C at 760 mmHg

Density

1.3±0.1 g/cm3

Exact Mass

445.152527

Flash Point

367.3±31.5 °C

Index of Refraction

1.620

LogP

5.78

Molecular Formula

C26H23NO6

Molecular Weight

445.464

PSA

101.93000

Storage condition

2-8°C

Vapour Pressure

0.0±2.2 mmHg at 25°C

Spectrums of 86060-83-5

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 86060-83-5

Retrosynthesis analysis of 86060-83-5

Q&A for CAS 86060-83-5

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Download SDS of 86060-83-5

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Warning

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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