structure of 867160-71-2

Cis-3-(8-Amino-1-(2-Phenylquinolin-7-Yl)Imidazo[1,5-A]Pyrazin-3-Yl)-1-Methylcyclobutan-1-Ol(CAS 867160-71-2)

CAS No.: 867160-71-2 Brand: MolBest
M. Ft.: C26H23N5O Cat. No: G1395250
M. Wt.: 421.49 MDL: No record
Storage: -20°C Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
98%
Documents:COANMRSDS
RG 100MG In Stock 293 USD
98%
Documents:COANMRSDS
RG 1G In Stock 1101 USD
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Applications of 867160-71-2

Linsitinib has been investigated for various applications in oncology, particularly as a treatment option for cancers driven by IGF-1R signaling. Its main applications include:

  • Prostate Cancer: Demonstrated potential in delaying progression in castration-resistant cases.
  • Non-Small Cell Lung Cancer: Used in combination therapies to overcome resistance mechanisms.
  • Thyroid Eye Disease: Recently evaluated for safety and efficacy in clinical trials targeting this condition.

Physical and chemical properties of 867160-71-2

Acidity coefficient

14.84±0.40(Predicted)

Density

1.4±0.1 g/cm3

Exact Mass

421.190247

Index of Refraction

1.748

LogP

3.23

Melting Point

>175°C (dec.)

Molecular Formula

C26H23N5O

Molecular Weight

421.494

PSA

89.33000

Solubility

Soluble in DMSO (up to 30 mg/ml)

Stability

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.

Storage condition

-20℃

Spectrums of 867160-71-2

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 867160-71-2

Retrosynthesis analysis of 867160-71-2


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