structure of 89-25-8

3-Methyl-1-phenyl-2-pyrazoline-5-one

CAS No.: 89-25-8 Brand: MolBest
M. Ft.: C10H10N2O Cat. No: G9247531
M. Wt.: 174.2 MDL: MFCD00003138
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
99% RG 25G In Stock 3 USD
99% RG 100G In Stock 5 USD
99% RG 2.5KG In Stock 46 USD
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Applications of 89-25-8

Edaravone is primarily used in medical settings for its neuroprotective effects. Its applications include:

  • Treatment of Amyotrophic Lateral Sclerosis: Approved in several countries for managing this progressive neurodegenerative disease.
  • Cerebral Ischemia: Utilized in conditions where oxidative stress plays a role in neuronal damage.
  • Radioprotection: Investigated for potential use as a radioprotective agent due to its ability to scavenge free radicals generated during radiation exposure.

Biological Activity of 89-25-8

The biological activity of edaravone is largely attributed to its antioxidant properties. It has been shown to inhibit lipid peroxidation and suppress endothelial cell damage induced by lipid peroxides. Furthermore, edaravone may possess anti-inflammatory effects, as it inhibits neutrophil activation and reduces the expression of inducible nitric oxide synthase and neuronal nitric oxide synthase in animal models. Its unique mechanism allows it to offer neuroprotection in conditions associated with oxidative stress, such as cerebral ischemia.

NMR spectrum of 89-25-8

Physical sample testing spectrum (NMR) of 89-25-8

Safety Information of 89-25-8

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H412 Harmful to aquatic life with long lasting effects

Safety Data Sheet

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Purchase Instructions of 89-25-8

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