2-Bromobenzenesulfonamide

2-Bromobenzenesulfonamide serves multiple purposes:

• Chemical Synthesis: It acts as a versatile precursor for synthesizing benzosultams, which are important in medicinal chemistry.
• Biological Research: Its role as a carbonic anhydrase inhibitor makes it valuable in studies related to cancer biology and enzyme inhibition.

2-Bromobenzenesulfonamide exhibits significant biological activity, particularly as an inhibitor of carbonic anhydrase IX, an enzyme often overexpressed in solid tumors. This inhibition affects pH regulation within tumor cells and has been linked to antiproliferative effects in various cancer cell lines, such as MDA-MB-231 and MCF-7. The compound induces apoptosis and alters cellular signaling pathways, highlighting its potential as a therapeutic agent in oncology.

The mechanism involves binding to the active site of carbonic anhydrase IX, preventing its normal function. This interaction can lead to changes in gene expression and cellular processes that contribute to tumor growth and survival.

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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

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