structure of 941678-49-5

Ruxolitinib(CAS 941678-49-5)

CAS No.: 941678-49-5 Brand: MolBest
M. Ft.: C17H18N6 Cat. No: G8349075
M. Wt.: 306.37 MDL: MFCD12031592
Storage: 2-8°C Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
98%
Documents:COANMRLCMSSDS
RG 100MG In Stock 27 USD
98%
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RG 250MG In Stock 31 USD
98%
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RG 1G In Stock 84 USD
98%
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RG 5G In Stock 292 USD
98%
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RG 25G In Stock 2424 USD
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Physical and chemical properties of 941678-49-5

Acidity coefficient

11.63±0.50(Predicted)

Boiling Point

592.6±50.0 °C at 760 mmHg

Density

1.4±0.1 g/cm3

Exact Mass

306.159302

Flash Point

312.2±30.1 °C

Index of Refraction

1.747

LogP

log Kow = 2.09 (est)

Melting Point

84-89°C

Molecular Formula

C17H18N6

Molecular Weight

306.365

PSA

83.18000

Stability

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Storage condition

2-8°C

Vapour Pressure

1.27X10-10 mm Hg at 25 °C (est)

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Spectrums of 941678-49-5

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 941678-49-5

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Hazard Statements

H361 Suspected of damaging fertility or the unborn child
H373 May causes damage to organs through prolonged or repeated exposure

Safety Data Sheet

Q&A for CAS 941678-49-5

1. How can I verify product quality?
Every batch is tested in accordance with ISO 9001 requirements. We provide a Certificate of Analysis (COA), NMR spectrum, purity report, and test methods with each shipment. Third-party retesting is supported, and we offer a full refund if our data is incorrect.

2. What is the delivery time?
Orders are shipped on the second business day via FedEx, DHL, or UPS. International deliveries typically arrive within 7 business days (subject to customs clearance).

3. What if the received product doesn’t meet quality standards?
If the product does not match the COA or has a quality issue, we will issue a full refund or replacement upon verification.

4. Are hazardous labels included? How is safe shipping ensured?
Hazardous products are labeled and packaged in compliance with international regulations and shipped with an up-to-date Safety Data Sheet (SDS) to ensure safe and compliant transport.

5. Do you offer technical support?
Yes. Our technical team is available to assist with questions about product use, storage, purity requirements, applications, and more.

6. Are volume discounts available?
Yes. We offer competitive pricing for bulk orders. Please submit a quotation request, and we’ll provide a customized offer.

7. Do you provide samples?
Yes, samples are available for select products for testing and validation. Please submit a sample request or contact our sales team to confirm availability and specifications.

8. Do you have products in stock?
Items marked “In Stock” on our website are ready for immediate shipment, usually within 1–2 business days. Large packs or custom specifications require lead time confirmation.

9. Can you customize purity or packaging?
Yes. We support customization of purity, packaging size, and special testing requirements. Please share your detailed needs, and we’ll provide a solution.

10. Is the COA consistent with the shipped batch?
Yes. The COA provided with your shipment matches the actual batch and includes the batch number. COAs shown online are for reference or from previous batches.

11. Do you support long-term supply agreements?
Yes. We offer stable batch consistency, pricing agreements, and safety stock options for long-term customers to ensure uninterrupted supply.

12. What payment methods do you accept?
We accept bank transfer (T/T), PayPal, and other methods. Credit terms may be available for qualified long-term partners.

Applications of 941678-49-5

Ruxolitinib is primarily indicated for:

  • Myelofibrosis: It helps reduce spleen size and improve symptoms.
  • Polycythemia Vera: Used when patients do not respond adequately to hydroxyurea.
  • Graft-Versus-Host Disease: Effective in steroid-refractory cases following allogeneic stem cell transplantation.

Emerging research suggests potential applications in other conditions, including autoimmune diseases and certain types of cancer.

Retrosynthesis analysis of 941678-49-5

  • Route#1

    Cas:1236033-03-6
    Cas:941678-49-5
  • Route#2

    Cas:941685-40-1
    Cas:941678-49-5
  • Route#3

    Cas:941678-49-5

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