structure of 943319-70-8

3-(Imidazo[1,2-B]Pyridazin-3-Ylethynyl)-4-Methyl-N-(4-((4-Methylpiperazin-1-Yl)Methyl)-3-(Trifluoromethyl)Phenyl)Benzamide(CAS 943319-70-8)

CAS No.: 943319-70-8 Brand: MolBest
M. Ft.: C29H27F3N6O Cat. No: G3985948
M. Wt.: 532.56 MDL: No record
Storage: -20°C Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
98%
Documents:COANMRSDS
RG 100MG In Stock 32 USD
98%
Documents:COANMRSDS
RG 250MG In Stock 54 USD
98%
Documents:COANMRSDS
RG 1G In Stock 146 USD
98%
Documents:COANMRSDS
RG 5G In Stock 512 USD
98%
Documents:COANMRSDS
RG 25G In Stock 2502 USD
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Physical and chemical properties of 943319-70-8

Acidity coefficient

12.99±0.70(Predicted)

Decomposition

Dangerous products of decomposition: thermal ecomposition may produce toxic gases such as carbon monoxide, carbon dioxide, and nitrogen oxides.

Density

1.3±0.1 g/cm3

Exact Mass

532.219849

Index of Refraction

1.622

LogP

log Kow = 4.32 (est)

Melting Point

>160 °C

Molecular Formula

C29H27F3N6O

Molecular Weight

532.560

PSA

65.77000

Stability

Stable for 2 years from date? of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Storage condition

-20°C

Vapour Pressure

2.5X10-17 mm Hg at 25 °C (est)

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Spectrums of 943319-70-8

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 943319-70-8

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Pictograms

Signal Word

Danger

Hazard Statements

H301 Toxic if swallowed
H311 Toxic in contact with skin
H331 Toxic if inhaled
H360FD May damage fertility; May damage the unborn child
H372 Causes damage to organs through prolonged or repeated exposure

Safety Data Sheet

Q&A for CAS 943319-70-8

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Applications of 943319-70-8

Ponatinib is primarily used in oncology for treating chronic myeloid leukemia and Philadelphia-positive acute lymphoblastic leukemia, particularly in patients who have developed resistance to other treatments due to mutations in the BCR-ABL gene. It is also being investigated for its potential use in other malignancies where tyrosine kinases play a critical role.

Retrosynthesis analysis of 943319-70-8

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