structure of 953769-46-5

4-((2-(((1R,2R)-2-Hydroxycyclohexyl)Amino)Benzo[D]Thiazol-6-Yl)Oxy)-N-Methylpicolinamide(CAS 953769-46-5)

CAS No.: 953769-46-5 Brand: MolBest
M. Ft.: C20H22N4O3S Cat. No: G3983695
M. Wt.: 398.48 MDL: MFCD28142668
Storage: 2-8°C Use: For laboratory research use only
Purity Grade Package Stock Price Quantity
98%
Documents:COANMRSDS
RG 250MG In Stock 247 USD
98%
Documents:COANMRSDS
RG 1G In Stock 668 USD
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Physical and chemical properties of 953769-46-5

Acidity coefficient

13.92±0.46(Predicted)

Density

1.4±0.1 g/cm3

Exact Mass

398.141266

Index of Refraction

1.693

LogP

2.50

Molecular Formula

C20H22N4O3S

Molecular Weight

398.479

PSA

127.84000

Storage condition

-20℃

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Spectrums of 953769-46-5

Attention:
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Physical sample testing spectrum (NMR) of 953769-46-5

Q&A for CAS 953769-46-5

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Applications of 953769-46-5

BLZ945 has potential applications in oncology, particularly for treating cancers associated with bone metastasis. By inhibiting CSF1R, it aims to reduce osteoclast-mediated bone resorption and alleviate skeletal-related complications in cancer patients. Furthermore, its ability to selectively target tumor-associated macrophages enhances its therapeutic profile in cancer treatment. Research is ongoing to explore its efficacy in combination therapies with other agents like zoledronate for improved outcomes in metastatic bone disease.

Retrosynthesis analysis of 953769-46-5


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