5-(4-((6-Hydroxy-2,5,7,8-Tetramethylchroman-2-Yl)Methoxy)Benzyl)Thiazolidine-2,4-Dione
| Purity | Grade | Package | Stock | Price | Quantity |
|---|---|---|---|---|---|
| 98% | RG | 100MG | In Stock | 309 USD | |
| 98% | RG | 250MG | In Stock | 747 USD | |
| 98% | RG | 1G | In Stock | 1478 USD | |
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NMR spectrum of 97322-87-7
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Applications of 97322-87-7
Troglitazone was primarily used for managing type 2 diabetes mellitus due to its ability to improve insulin sensitivity. Although it is no longer available for clinical use due to safety concerns, research continues into its potential applications in other areas:
- Investigational Research: Studies are ongoing into troglitazone's mechanisms that could inform new therapies for diabetes or other metabolic disorders.
- Cancer Research: Some derivatives of troglitazone have been explored for their antiproliferative effects in cancer cell lines.
Biological Activity of 97322-87-7
Troglitazone exhibits significant biological activity through its mechanism of action involving PPAR activation. By binding to PPARγ and PPARα, it enhances insulin sensitivity and decreases hepatic glucose output while promoting glucose disposal in skeletal muscle. This dual action helps to lower blood glucose levels effectively. Additionally, troglitazone has anti-inflammatory properties, potentially reducing inflammation through inhibition of nuclear factor kappa-B (NF-κB) activity.
Despite its effectiveness, troglitazone was associated with severe hepatotoxicity, leading to its withdrawal from the market in 2000 after reports of liver injury surfaced.
Bulk Packaging Price Explanation of 97322-87-7
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Purchase Instructions of 97322-87-7
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.
These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.
Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.
