N-(3,5-Bistrifluoromethylphenyl)-5-Chloro-2-Hydroxybenzamide
| Purity | Grade | Package | Stock | Price | Quantity |
|---|---|---|---|---|---|
| 98% | RG | 1G | In Stock | 450 USD | |
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Applications of 978-62-1
IMD-0354 has potential applications in cancer treatment due to its ability to modulate NF-κB signaling pathways. Its role as an apoptosis inducer makes it relevant in therapeutic strategies targeting various malignancies, including chronic lymphocytic leukemia and melanoma. Additionally, its inhibitory effects on glutamine metabolism suggest applications in metabolic reprogramming strategies for cancer therapy.
Biological Activity of 978-62-1
IMD-0354 exhibits significant biological activity, particularly in inducing apoptosis in various cancer cell lines. It has been shown to inhibit NF-κB activation, which is crucial for cell survival and proliferation. In chronic lymphocytic leukemia cells, IMD-0354 induced apoptosis and reduced DNA-binding activity of NF-κB in a dose-dependent manner. Furthermore, it has demonstrated the ability to inhibit glutamine uptake, leading to reduced growth in melanoma cells and other tumor-derived cell lines. This compound's effects on cellular metabolism and signaling pathways make it a promising candidate for cancer therapy.
NMR spectrum of 978-62-1
Safety Information of 978-62-1
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Bulk Packaging Price Explanation of 978-62-1
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Purchase Instructions of 978-62-1
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