structure of 98-18-0

3-Aminobenzenesulfonamide

CAS No.: 98-18-0 Brand: MolBest
M. Ft.: C6H8N2O2S Cat. No: G6012894
M. Wt.: 172.2 MDL: MFCD00035781
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
98% RG 5G In Stock 5 USD
98% RG 500G In Stock 174 USD
98% RG 2.5KG In Stock 1151 USD
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Applications of 98-18-0

3-Aminobenzenesulfonamide is used in various fields:

  • Pharmaceuticals: It serves as a precursor for synthesizing drugs that inhibit carbonic anhydrases, which can be beneficial in treating conditions like glaucoma and certain cancers.
  • Chemical Research: It is utilized in the study of enzyme inhibition mechanisms and drug design.
  • Laboratory Reagents: The compound is used in various chemical syntheses and analytical procedures due to its reactive functional groups.

Biological Activity of 98-18-0

3-Aminobenzenesulfonamide exhibits significant biological activity, primarily as an inhibitor of carbonic anhydrases. These enzymes are crucial for maintaining acid-base balance and facilitating gas exchange in biological systems. The compound has demonstrated potent inhibitory effects against several isoforms, including:

  • Carbonic Anhydrase I (CA I)
  • Carbonic Anhydrase II (CA II)
  • Tumor-associated Carbonic Anhydrase IX (CA IX)
  • Tumor-associated Carbonic Anhydrase XII (CA XII)

Inhibition studies reveal that certain derivatives possess nanomolar potency against CA IX and CA XII, making them potential candidates for cancer treatment.

NMR spectrum of 98-18-0

Physical sample testing spectrum (NMR) of 98-18-0

Safety Information of 98-18-0

Pictograms

Signal Word

Warning

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Safety Data Sheet

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Bulk Packaging Price Explanation of 98-18-0

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Purchase Instructions of 98-18-0

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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