structure of 980-21-2

Dityrosine Dihydrochloride

CAS No.: 980-21-2 Brand: MolBest
M. Ft.: C18H20N2O6 Cat. No: G2290676
M. Wt.: 360.37 MDL: No record
Storage: 2-8°C
Purity Grade Package Stock Price Quantity
95% RG 100MG In Stock 474 USD
95% RG 250MG In Stock 977 USD
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Applications of 980-21-2

Dityrosine has several applications across various fields:

  • Biomarker for Disease: Its presence serves as an indicator of oxidative stress in biological samples, aiding in the diagnosis of conditions like Alzheimer’s disease and Parkinson’s disease.
  • Fluorescent Probe: Dityrosine's intrinsic fluorescence allows it to be used as a probe for studying protein structures and interactions.
  • Material Science: In biomaterials, dityrosine cross-linking contributes to the mechanical properties of elastomeric materials.

Biological Activity of 980-21-2

Dityrosine serves as a biomarker for oxidative stress and has been implicated in various pathologies, including aging and neurodegenerative diseases. The presence of dityrosine cross-links in proteins is associated with structural changes that can compromise their function. For instance:

  • Enzymatic Activity: Dityrosine cross-linking may reduce the enzymatic activity of proteins like ribonuclease A while maintaining some functional capacity in others like alpha-crystallin, which retains its chaperone-like properties despite dimerization.
  • Structural Stability: Proteins with dityrosine cross-links often exhibit decreased thermal stability compared to their non-cross-linked counterparts.

NMR spectrum of 980-21-2

Physical sample testing spectrum (NMR) of 980-21-2

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Purchase Instructions of 980-21-2

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