structure of 98273-47-3

2-Cyanoisonicotinamide

CAS No.: 98273-47-3 Brand: MolBest
M. Ft.: C7H5N3O Cat. No: G8840481
M. Wt.: 147.13 MDL: No record
Storage: No record
Purity Grade Package Stock Price Quantity
97% RG 1G In Stock 165 USD
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Applications of 98273-47-3

2-Cyanoisonicotinamide has several applications, including:

  • Drug Development: It serves as a building block for creating peptide inhibitors against viral targets.
  • Chemical Biology: Its role in bioconjugation allows researchers to design stable cyclic peptides that can be used in therapeutic contexts.
  • Synthetic Chemistry: The compound's reactivity makes it useful in various organic synthesis applications, particularly those involving nitriles and thiols.

Biological Activity of 98273-47-3

The biological activity of 2-cyanoisonicotinamide has been explored extensively, particularly in the context of antiviral research. Studies have demonstrated that it can serve as a precursor for potent peptide inhibitors targeting viral proteases, such as those from the Zika virus. The incorporation of 2-cyanoisonicotinamide into peptide sequences enhances their inhibitory potency and specificity.

Moreover, the compound's ability to form stable cyclic peptides through its reactions with cysteine residues contributes to its potential as a scaffold for drug design, allowing for improved pharmacokinetic properties and reduced degradation in biological environments.

NMR spectrum of 98273-47-3

Physical sample testing spectrum (NMR) of 98273-47-3

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