structure of 98418-47-4

Metoprolol Succinate

CAS No.: 98418-47-4 Brand: MolBest
M. Ft.: 2C15H25NO3.C4H6O4 Cat. No: G2109397
M. Wt.: 652.82 MDL: No record
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
99% RG 1G In Stock 6 USD
99% RG 5G In Stock 16 USD
99% RG 100G In Stock 131 USD
99% RG 500G In Stock 510 USD
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Applications of 98418-47-4

Metoprolol succinate is widely used in clinical practice for:

  • Hypertension Management: It helps lower blood pressure in individuals with hypertension.
  • Heart Failure Treatment: It is indicated for stable, symptomatic heart failure, particularly in patients with ischemic or hypertensive origins.
  • Angina Pectoris: Used to alleviate chest pain associated with angina.

Additionally, it has been studied for its role in reducing mortality rates in patients with chronic heart failure.

Biological Activity of 98418-47-4

Metoprolol succinate exerts its pharmacological effects by selectively blocking beta-1 adrenergic receptors located primarily in cardiac tissues. This action leads to:

  • Reduced Heart Rate: It decreases the heart rate by inhibiting the effects of adrenaline and noradrenaline.
  • Decreased Cardiac Output: By reducing myocardial contractility, it lowers cardiac output.
  • Renin Inhibition: It suppresses renin release from the kidneys, contributing to decreased blood pressure.

The extended-release formulation allows for more stable plasma levels of the drug, minimizing peaks and troughs associated with immediate-release formulations.

NMR spectrum of 98418-47-4

Physical sample testing spectrum (NMR) of 98418-47-4

Safety Information of 98418-47-4

Pictograms

Signal Word

Danger

Hazard Statements

H302 Harmful if swallowed
H370 Causes damage to organs
H412 Harmful to aquatic life with long lasting effects

Safety Data Sheet

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Bulk Packaging Price Explanation of 98418-47-4

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Purchase Instructions of 98418-47-4

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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