N,N'-Bis(9-Fluorenylmethyloxycarbonyl)-L-Histidine

Fmoc-His(Fmoc)-OH is widely used in:

• Solid-Phase Peptide Synthesis (SPPS): Its dual protection allows for efficient assembly of peptides while minimizing racemization and epimerization.
• Drug Development: Peptides containing histidine are explored for therapeutic applications due to their biological activities.
• Bioconjugation: The compound can serve as a building block for creating complex biomolecules through conjugation techniques.

Histidine plays a critical role in various biological processes, including enzyme catalysis and metal ion coordination. The biological activity of peptides containing Fmoc-His(Fmoc)-OH can be influenced by:

• Enzymatic Function: Histidine residues are often found at active sites of enzymes, where they participate in proton transfer and substrate binding.
• Metal Binding: Histidine has a unique ability to coordinate with metal ions, which is essential for the function of metalloproteins.
• Peptide Stability: The presence of dual Fmoc groups can enhance the stability of synthesized peptides against hydrolysis and degradation during storage and application.

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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

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