4-Nitro-o-Phenylenediamine

The primary application of 4-nitro-o-phenylenediamine is in the cosmetic industry as a component of oxidation hair dyes. It is used at concentrations typically not exceeding 1% in formulations, which translates to about 0.5% upon application after mixing with hydrogen peroxide. Beyond cosmetics, its mutagenic properties have made it a subject of study in toxicology and environmental science.

The biological activity of 4-nitro-o-phenylenediamine has been extensively studied, particularly concerning its mutagenic properties. Research indicates that it induces mutations in Salmonella typhimurium and mouse lymphoma cells without metabolic activation. The compound has been shown to increase revertant colonies significantly when tested under controlled conditions, suggesting a clear mutagenic effect. Additionally, it is considered moderately toxic by ingestion and can cause irritation to the skin, eyes, and respiratory tract.

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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

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