structure of 99-73-0

2,4′-Dibromoacetophenone

CAS No.: 99-73-0 Brand: MolBest
M. Ft.: C8H6Br2O Cat. No: G2033293
M. Wt.: 277.94 MDL: MFCD00000200
Storage: 2-8°C
Purity Grade Package Stock Price Quantity
98% RG 25G In Stock 15 USD
98% RG 100G In Stock 54 USD
98% RG 500G In Stock 241 USD
98% RG 2.5KG In Stock 1206 USD
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Applications of 99-73-0

The applications of 2,4'-dibromoacetophenone are diverse:

  • Analytical Chemistry: It is used in the identification and analysis of carboxylic acids.
  • Biological Research: As an inhibitor of glycogen synthase kinase 3 beta, it plays a role in studies related to cell signaling and cancer research.
  • Organic Synthesis: Its utility extends to organic synthesis where it acts as a protective group for phenols and carboxylic acids during various reactions.

Biological Activity of 99-73-0

The biological activity of 2,4'-dibromoacetophenone has been highlighted primarily through its role as an inhibitor of glycogen synthase kinase 3 beta. This inhibition has implications in various cellular processes, including those related to cancer and neurodegenerative diseases. The compound exhibits an IC50 value of approximately 0.5 μM, indicating its potency as a non-ATP competitive inhibitor. Additionally, studies suggest that it may have applications in protecting phenolic compounds from oxidation.

Safety Information of 99-73-0

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Hazard Statements

H314 Causes severe skin burns and eye damage

Safety Data Sheet

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Purchase Instructions of 99-73-0

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