structure of 99247-33-3

Proglumide Sodium

CAS No.: 99247-33-3 Brand: MolBest
M. Ft.: C18H25N2NaO4 Cat. No: G1972038
M. Wt.: 356.39 MDL: No record
Storage: Store under inert gas.
Purity Grade Package Stock Price Quantity
98% RG 100MG In Stock 72 USD
98% RG 250MG In Stock 135 USD
98% RG 1G In Stock 487 USD
98% RG 5G In Stock 2047 USD
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Applications of 99247-33-3

Proglumide sodium salt has several applications, primarily in research:

  • Pain Research: Used to study mechanisms underlying pain perception and modulation.
  • Anxiety Studies: Investigated for its effects on anxiety-related behaviors due to its interaction with cholecystokinin.
  • Pharmacological Research: Assists in understanding receptor interactions and drug development targeting cholecystokinin pathways.

Biological Activity of 99247-33-3

Proglumide sodium salt exhibits significant biological activity as a cholecystokinin antagonist. It has been shown to inhibit the effects of cholecystokinin on pain perception, effectively abolishing nocebo-induced hyperalgesia. This suggests that it plays a role in modulating pain pathways by interfering with cholecystokinin signaling, which is implicated in anxiety and stress responses. Furthermore, proglumide has been found to enhance the analgesic effects of opioids and placebo treatments, indicating its potential utility in pain management strategies.

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Purchase Instructions of 99247-33-3

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

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