9-Methyl-3-((2-Methyl-1H-Imidazol-1-Yl)Methyl)-2,3-Dihydro-1H-Carbazol-4(9H)-One
| Purity | Grade | Package | Stock | Price | Quantity |
|---|---|---|---|---|---|
| 99% | RG | 1G | In Stock | 11 USD | |
| 99% | RG | 5G | In Stock | 33 USD | |
| 99% | RG | 25G | In Stock | 156 USD | |
| 99% | RG | 100G | In Stock | 570 USD | |
| 99% | RG | 500G | In Stock | 2755 USD | |
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Applications of 99614-02-5
Ondansetron is primarily used in clinical settings for:
- Prevention of chemotherapy-induced nausea and vomiting.
- Prevention of postoperative nausea and vomiting.
- Management of nausea associated with radiation therapy.
It may also be employed off-label for other conditions as deemed appropriate by healthcare providers.
Biological Activity of 99614-02-5
The primary mechanism of action for ondansetron involves antagonism of the 5-HT3 receptors located in both the central nervous system and peripheral nervous system. By blocking these receptors, ondansetron effectively inhibits the vomiting reflex triggered by serotonin release in response to chemotherapeutic agents. The drug exhibits both central and peripheral effects; central effects are mediated through the chemoreceptor trigger zone in the medulla oblongata while peripheral effects occur via vagal afferents in the gastrointestinal tract.
PharmacodynamicsOndansetron has a high selectivity for 5-HT3 receptors compared to dopamine receptors, which contributes to its efficacy as an antiemetic agent. Common side effects include headache, constipation, diarrhea, and dizziness, while serious side effects may involve QT prolongation and allergic reactions.
NMR spectrum of 99614-02-5
Safety Information of 99614-02-5
Download COA of 99614-02-5
Bulk Packaging Price Explanation of 99614-02-5
Please email your required order quantity and detailed technical specifications to sales@.
Our sales team will promptly prepare an accurate quotation for your bulk order and provide a comprehensive pricing proposal.
Purchase Instructions of 99614-02-5
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.
These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.
Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.
