24-Norursodeoxycholic Acid

24-Norursodeoxycholic acid has several potential applications in medicine:

• Treatment of liver diseases: It is being explored for its efficacy in treating cholestatic liver diseases and conditions like primary sclerosing cholangitis.
• Anti-inflammatory agent: Due to its ability to modulate immune responses, it may be beneficial in managing inflammatory conditions related to liver dysfunction.
• Research tool: Its unique properties make it a valuable compound for studying bile acid metabolism and immune modulation in various experimental models.

The biological activity of 24-norursodeoxycholic acid is primarily linked to its anti-inflammatory and immunomodulatory effects. It has been shown to reduce the number of hepatic immune cells, including CD8+ T cells, thereby alleviating inflammation in conditions such as primary sclerosing cholangitis. The compound modulates the mTORC1 signaling pathway in CD8+ T cells, influencing their metabolic state and effector functions. Additionally, it exhibits protective effects against alcohol-related liver disease by promoting an anti-inflammatory macrophage phenotype.

Please email your required order quantity and detailed technical specifications to sales@.
Our sales team will promptly prepare an accurate quotation for your bulk order and provide a comprehensive pricing proposal.

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.