structure of 99755-59-6

Rotigotine

CAS No.: 99755-59-6 Brand: MolBest
M. Ft.: C19H25NOS Cat. No: G5531627
M. Wt.: 315.47 MDL: MFCD00870193
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
99% RG 100MG In Stock 53 USD
99% RG 250MG In Stock 100 USD
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Applications of 99755-59-6

Rotigotine is primarily indicated for:

  • Parkinson's Disease: It helps alleviate motor symptoms by stimulating dopamine receptors.
  • Restless Legs Syndrome: It provides relief from discomfort associated with this condition.

Additionally, due to its action on various neurotransmitter systems, rotigotine has been explored for potential use in treating depression and other mood disorders.

Biological Activity of 99755-59-6

Rotigotine acts as an agonist at all five dopamine receptor subtypes (D1-D5), exhibiting the highest affinity for the D3 receptor. It also shows antagonist activity at α-2 adrenergic receptors and partial agonist activity at 5-HT1A receptors. This broad receptor activity contributes to its efficacy in treating motor symptoms associated with Parkinson's disease and may also provide antidepressant effects.

Affinity Profile
Receptor TypeAffinity (K_i in nM)
D183
D213.5
D30.71
D43.9
D55.4

NMR spectrum of 99755-59-6

Physical sample testing spectrum (NMR) of 99755-59-6

Safety Information of 99755-59-6

Pictograms

Signal Word

Warning

Hazard Statements

H302 Harmful if swallowed
H336 May cause drowsiness or dizziness
H361 Suspected of damaging fertility or the unborn child
H362 May cause harm to breast-fed children
H413 May cause long lasting harmful effects to aquatic life

Safety Data Sheet

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Bulk Packaging Price Explanation of 99755-59-6

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Purchase Instructions of 99755-59-6

All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

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