structure of 99896-85-2

Arginyl-Glycyl-Aspartic Acid

CAS No.: 99896-85-2 Brand: MolBest
M. Ft.: C12H22N6O6 Cat. No: G1208606
M. Wt.: 346.34 MDL: No record
Storage: -20°C,Under inert gas.
Purity Grade Package Stock Price Quantity
98% RG 25MG In Stock 29 USD
98% RG 100MG In Stock 86 USD
98% RG 250MG In Stock 163 USD
98% RG 1G In Stock 468 USD
98% RG 5G In Stock 1455 USD
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Applications of 99896-85-2

Arg-Gly-Asp has numerous applications across various fields:

  • Biomedical Research: Used extensively in studies involving cell adhesion and migration.
  • Tissue Engineering: Incorporated into scaffolds to promote cell attachment and proliferation.
  • Drug Delivery Systems: Utilized as targeting ligands for delivering therapeutic agents specifically to cells expressing integrin receptors.
  • Diagnostic Imaging: Radiolabeled versions of Arg-Gly-Asp are employed in positron emission tomography for imaging tumors.

Biological Activity of 99896-85-2

Arg-Gly-Asp exhibits significant biological activity through its role as an integrin-binding motif. It is known to mediate various cellular processes:

  • Cell Adhesion: The tripeptide promotes adhesion of cells to the extracellular matrix by binding to specific integrin receptors.
  • Cell Migration: It plays a role in guiding cell movement during wound healing and tissue repair.
  • Apoptosis: Certain studies indicate that Arg-Gly-Asp peptides can induce apoptosis in cells lacking survival signals by activating pro-caspase-3 pathways.
  • Tumor Targeting: Arg-Gly-Asp has been utilized in cancer therapies for targeting tumor vasculature through integrin αvβ3.

NMR spectrum of 99896-85-2

Physical sample testing spectrum (NMR) of 99896-85-2

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Purchase Instructions of 99896-85-2

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