structure of 1500-85-2

4-Amino-7H-Pyrrolo[2,3-d]Pyrimidine

CAS No.: 1500-85-2 Brand: MolBest
M. Ft.: C6H6N4 Cat. No: G5177234
M. Wt.: 134.14 MDL: MFCD01686848
Storage: Store in a cool,dry area.
Purity Grade Package Stock Price Quantity
97% RG 250MG In Stock 4 USD
97% RG 1G In Stock 5 USD
97% RG 5G In Stock 15 USD
97% RG 25G In Stock 42 USD
97% RG 100G In Stock 161 USD
97% RG 500G In Stock 788 USD
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Applications of 1500-85-2

The unique properties of 4-amino-7H-pyrrolo[2,3-d]pyrimidine make it suitable for various applications:

  • Pharmaceuticals: Due to its kinase inhibitory properties, it is being explored as a lead compound for developing anti-cancer drugs.
  • Chemical Probes: Its ability to modulate specific signaling pathways makes it useful in biochemical research for studying cellular processes.
  • Potential Therapeutics: The compound's derivatives are being investigated for their effectiveness against diseases such as malaria and cancer.

Biological Activity of 1500-85-2

Research indicates that 4-amino-7H-pyrrolo[2,3-d]pyrimidine exhibits significant biological activity, particularly as an inhibitor of protein kinases. For instance, it has been identified as a potential inhibitor of PfCDPK4 (Plasmodium falciparum calcium-dependent protein kinase), displaying promising inhibitory activity with IC50 values ranging from 0.210 to 0.530 μM. Additionally, derivatives of this compound have shown effectiveness against protein kinase B (Akt), indicating its potential in cancer therapy due to its ability to modulate signaling pathways involved in cell proliferation and survival.

NMR spectrum of 1500-85-2

Physical sample testing spectrum (NMR) of 1500-85-2

Safety Information of 1500-85-2

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Danger

Hazard Statements

H301 Toxic if swallowed

Safety Data Sheet

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Purchase Instructions of 1500-85-2

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