N-(Tert-Butyldimethylsilyl)-2,2,2-Trifluoro-N-Methylacetamide(CAS 77377-52-7)
| Purity | Grade | Package | Stock | Price | Quantity |
| 95% | RG | 1G | In Stock | 10 USD
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| 95% | RG | 5G | In Stock | 18 USD
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| 95% | RG | 25G | In Stock | 81 USD
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| 95% | RG | 100G | In Stock | 323 USD
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| 95% | RG | 500G | In Stock | 1550 USD
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Available NMR Spectrum
Verified In Stock
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Quality System
Applications of 77377-52-7
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Organic synthesis intermediate | Used as a silylation reagent to introduce the tert-butyldimethylsilyl (TBDMS) protecting group onto functional groups such as hydroxyl and amino groups |
| Chemical Research | Analytical reagent | Applied as a derivatization reagent in gas chromatography–mass spectrometry (GC-MS) analysis to enhance sample volatility and thermal stability |
| Pesticides | Pesticide synthesis intermediate | Used in synthesizing pesticide active ingredients containing silicon-based protecting groups to improve compound selectivity and stability |
| Materials Science | Functional material preparation | Employed as a functional additive in polymer synthesis to tailor polymer structure and properties |
| Biochemistry | Biomolecule modification | Applied for silylation modification of biomolecules such as peptides and nucleotides to enhance lipophilicity and metabolic stability |
Physical and chemical properties of 77377-52-7
Acidity coefficient |
-1.50±0.70(Predicted) |
|---|---|
Boiling Point |
182.6±35.0 °C at 760 mmHg |
BRN |
3606546 |
Density |
1.0±0.1 g/cm3 |
Exact Mass |
241.110977 |
Flash Point |
64.2±25.9 °C |
Index of Refraction |
1.400 |
LogP |
3.32 |
Molecular Formula |
C9H18F3NOSi |
Molecular Weight |
241.326 |
PSA |
20.31000 |
Sensitivity |
Moisture Sensitive |
Solubility |
sol most aprotic organic solvents. |
Storage condition |
2-8°C |
Vapour Pressure |
0.8±0.3 mmHg at 25°C |
Water Solubility |
decomposes |
Spectrums of 77377-52-7
1.The NMR spectrum displayed on the page is a pre-sale reference spectrum and may differ from that of the actual received batch.
2.The accompanying documentation will include the NMR spectrum and purity analysis data for the shipped batch.
Retrosynthesis analysis of 77377-52-7
Q&A for CAS 77377-52-7
1. How can I verify product quality?
Every batch of our Chemical Reagents is tested to meet ISO 9001 standards. We provide COA & NMR & SDS Provided with each shipment. Batch COA available for verification, and third-party retesting is supported. A full refund is offered if our data is incorrect.
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If your Lab Grade Chemical Reagents do not match the Batch COA available, we will issue a replacement or a full refund upon verification.
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Hazardous products are labeled and packaged following international regulations. We provide SDS Provided with all hazardous shipments to ensure safe and compliant transport.
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Yes. Our Lab Supplier team is available to assist with questions about product usage, storage, Lab Grade requirements, applications, and more.
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Yes. We support customization of Lab Grade purity, packaging size, and special testing requirements. Share your needs and we’ll provide a tailored solution.
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Yes. Batch COA available matches the actual shipment. COAs shown online are for reference or from previous batches.
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Yes. We offer Lab Supplier services for stable batch consistency, pricing agreements, and safety stock for long-term customers to ensure uninterrupted supply.
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Download SDS of 77377-52-7
Pictograms |
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|---|---|
Signal Word |
Warning |
Hazard Statements |
H226 Flammable liquid and vapor H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation |
Safety Data Sheet |
Download COA of 77377-52-7
Operate under the ISO 9001 system

